About the Bioinformatics Centre
|
|
The Bioinformatics Centre, Assam University, Silchar is directly sponsored by the Department of Biotechnology (DBT), Govt. of India to explore the bright new areas of Bioinformatics in data management, algorithm development and data mining.
The Centre was established in the year 2008 with full financial assistance from Department of Biotechnology, Govt. of India under DBT-BIF scheme. Since its birth it is actively associated with the popularizing Bioinformatics applications in Biological researches in Southern Assam and North East India as a whole. The Department of Life Science, Assam University took special initiative to establish this centre. In January 2009, the Bioinformatics Laboratory was inaugurated by the then Hon'ble Vice Chancellor Prof. Tapodhir Bhattacharjee.
The Centre organizes workshops, seminars, training programmes etc. from time to time for the popularization of Biology Teaching through Bioinformatics and also to generate awareness on Bioinformatics. Moreover, our Post Graduate Diploma in Bioinformatics (PGDBI) is a thoughtful career oriented programme.
. For more information and database access visit www.bioinfoaus.ac.in
Area of Specialization: Computer Aided Drug Designing is the main thrust area of the centre. The centre is actively engaged in research on Natural Product based Computer Aided Drug Designing.
|
Objectives |
| Being situated in one of remotest corners of the country, the main aim of the centre is to spread the knowledge of Bioinformatics in the region. Moreover carrying high quality research and developing products utilizing the knowledge of Bioinformatics and the natural resources of the region is one of the major objectives of the centre. |
Achievements at a glance |
a) Conducted several training programs on different arena of Bioinformatics.
b) Published several papers in High Quality pure Bioinformatics journals.
c) In November 2013, the centre organized a National Conference on Contemporary Bioinformatics Researches in India, which is first of its kind in entire North East.
d) Hosted the 6th NEBInet meet during 11-12 November 2013.
e) Developed and managing the website of the centre and few Biological databases.
f) Coordinates the e-Journals access facility in Assam University under DBT e-Library Consortium. |
| |
Current area of research |
Natural Product based Computer Aided Drug Designing is the main area of research in the centre. The natural products isolated from the important and endemic medicinal plants of this region are screened for their therapeutic activities to establish them as drug lead. |
| |
Databases/applications developed |
|
| |
Inter Institutional collaboration |
The center has strong collaboration with nearby Bioinformatics Centres as well as different departments of Tezpur University (Tezpur), Assam Agricultural University (Jorhat), IASST (Guwahati), NIELIT (Guwahati) etc. |
|
Recent publications |
From Bioinformatics Centre |
Arpita Das Choudhury, Manabendra Dutta Choudhury, Pankaj Chetia, Abhishek Chowdhury and Anupam Das Talukdar (2013). An In Silico Appraisal of Azoic and Disulphide Derivatives for Anticancer Activity Against HPV E6 Oncoprotein to Medicate Cervical Cancer. Combinatorial Chemistry & High Throughput Screening. 16(10). IF: 2.0 [PMID: 24164050]
|
Anupom Borah, Rajib Paul, Sabanum Choudhury, Amarendranath Choudhury, Anupam Das Talukdar, Bhuyan B, Manabendra Dutta Choudhury, Kochupurackal P Mohanakumar ( 2013): Neuroprotective Potential of Silymarin against CNS Disorders :Insight into the Pathways and Molecular Mechanisms of Action. CNS Neurosciences & Therapeutics 19: 847-853 . IF: 4.45 [PMID: 24118806]
|
Abhisek Choudhury, Poulami Paul, Manabendra Dutta Choudhury (2013) : High throughput screening of 7-methylpicene-1,2-diol as Arylamine N-acetyltransferase (NAT) inhibitor to establish a Isoniazid supplement in anti-tubercular therapy’. Combinatorial Chemistry & High Throughput Screening 16:721-725 IF: 2.0 [PMID: 23701008]
|
Abhishek Chowdhury, Paulomi Paul, Pankaj Chetia, Manabendra Dutta Choudhury (2013): Screening of Few Epoxides as mt-MAPK Inhibitor Preventing Granuloma Formation to Serve as Tubercular Antidote. Letters in Drug Design & Discovery 10:164-168. IF : 0.872
|
Manabendra Dutta Choudhury, Monjur Ahmed Laskar, Shuvasish Choudhury, Pankaj Chetia (2013): Molecular mechanism of analgesic action of solanoglycosydane – An in silico study. Asian Journal of Pharmaceutical and Clinical Research 6:80-82. IF: 0.7
|
Monjur Ahmed Laskar, Manabendra Dutta Choudhury, Pankaj Chetia (2013): Comparative analysis of activity of certain Flavonols against Angiotensin Converting Enzyme (ACE) for cardioprotective activity. Current Computer Aided Drug Design (Peer Review Completed). IF:1.54
|
Out of collaboration |
Budheswar Dehury, Mousumi Sahu, Jagajjit Sahu, Kishore Sarma, Priyabrata Sen, Mahendra K Modi, Madhumita Barooah, Manabendra D Choudhury (2013): Structural analysis and molecular dynamics simulations of novel δ-endotoxin Cry1Id from Bacillus thuringiensis to pave the way for development of novel fusion proteins against insect pests of crops. Journal of Molecular Modeling (In press). IF: 1.9 [PMID: 24154610]
|
Budheswar Dehury, Mousumi Sahu, Kishore Sarma, Jagajjit Sahu, Priyabrata Sen, Mahendra Kumar Modi, Gauri Dutta Sharma, Manabendra Dutta Choudhury, and Madhumita Barooah (2013): Molecular Phylogeny, Homology Modeling, and Molecular Dynamics Simulation of Race-Specific Bacterial Blight Disease Resistance Protein (xa5) of Rice: A Comparative Agriproteomics Approach. OMICS: A Journal of Integrative Biology 17: 423-438. IF: 2.73 [PMID: 23758479]
|
Budheswar Dehury, Mousumi Sahu, Mahesh C Patra, Kishore Sarma, Jagajjit Sahu, Priyabrata Sen, Mahendra K Modi, Manabendra D Choudhury, Madhumita Barooah (2013): Insights into the structure-function relationship of disease resistance protein HC TR in maize (Zea mays L.): A computational structural biology approach. Journal of Molecular Graphics and Modelling 45:50-67. IF: 2.35 [PMID: 24004829]
|
Where Bioinformatics Centre has been acknowledged |
10. Paulomi Paul, Abhishek Chowdhury, Deepa Nath And Mrinal Kanti Bhattacharjee (2013): Antimicrobial efficacy of orchid extracts as potential inhibitors of antibiotic resistant strains of Escherichia coli. Asian Journal of Pharmaceutical and Clinical Research 6:108-111. IF: 0.7
|
Sanjoy Singh Ningthoujam, Anupam Das Talukdar, Potsangbam Kumar Singh, Manabendra Dutta Choudhury (2013): Traditional uses of herbal vapour therapy in Manipur, north east india : an ethnopharmacological survey . Journal of Ethnopharmacology 147:136-147. IF: 3.7 [PMID: 23473866]
|
Sushmita Nath, Manabendra Dutta Choudhury, Shubhadeep Roychoudhury, Anupam Das Talukdar, Man Mohan Misro (2013) : Male contraceptive efficacy of Ricinus communis L. extract. Journal of Ethnopharmacology 149:328-334. IF: 3.7 [PMID: 23850709]
|
|
|
|
About the Institution
|
TAssam University came into existence through Assam (Central) University Act, 1989(Established under an Act of Parliament) . It was established in 1994,since then the University is steadily becoming an excellent centre of learning.
The campus, situated in Dargakona, about 20 kms from Silchar, is set amid sprawling hillocks, a typical landscape in the North East. The campus in an area of 600 acres surrounded by lakes and mountains provides an ideal environment for academic pursuit.
Drawing its 300 plus faculty from many disciplines, from all over the country, the university sustains a multidisciplinary approach to higher education.
The University has sixteen Schools on major disciplines. There are 35 Departments under these sixteen Schools.
|
| |
 |
Delegates of 6th NEBInet Meet held at Bioinformatics Centre, Assam University
|
| |
Infrastructure facilites |
Hardware facilities: |
IBM System X 3650 High End Server |
1 No. |
IBM System X 3650 Medium End Server |
1 No. |
Dell Optiplex Desktop PCs (Win Vista) |
10 Nos. |
HP Pavillion P6000 Desktop PCs (Windows 7) |
5 Nos. |
APC 3KVA Online UPS (1hr Backup) |
2 Nos. |
42” SHARP Professional Display Unit |
1 No. |
SHARP AR-5516 Photocopier cum Printer |
1 No. |
HP Inkjet Color Printer |
1 No. |
HP Flatbed Scanjet |
1 No. |
HP Color Laserjet CP1515n |
1 No. |
HP Scanjet N6350 |
1 No. |
Sony NEX-5 DSLR Camera |
1 No. |
Sony Handycam |
1 No. |
Laserjet Printer |
1 No. |
Toshiba Multimedia Projectors |
2 Nos. |
|
| |
Software facilities |
Windows 2008 Server SE |
1 No. |
RedHat Enterprise Linux 5.0 SE |
1 No. |
MS SQL Server 2008 SE |
1 No. |
MS SQL Server 2003 |
2 No. |
MS Visual Studio 2008 |
1 No. |
Statistica |
12 Nos. |
MS Office Professional 2007 |
10 Nos. |
Lead IT with FlexX and CORINA-F |
1 No. |
Genious Pro 5.6.2 |
2 Nos. |
PAUP 4.0 |
1 No. |
Chem Bio Office 2012 |
1 No. |
Statistica 12 |
1 No. |
MATLAB R2012a
» Bioinformatics Toolbox
» Statistics Toolbox
» Simbiology Toolbox
» Neural Network Toolbox |
2 Nos. each |
|
|
AutoDock 4.2 with PMV |
OS |
AutoDock Vina |
OS |
Modeller |
OS |
Dock |
OS |
Hex |
OS |
Chimera |
OS |
Rasmol |
OS |
BioEdit |
OS |
MEGA |
OS |
PHYLIP |
OS |
Clustal W / Clustal X |
OS |
Gromacs |
OS |
|
| |
Faculty members |
| |
| There is no permanent faculty in the Bioinformatics Centre of Assam University. However, Prof. M. Dutta Choudhury and Dr. Anupam Das Talukdar of the Department of Life Science & Bioinformatics of Assam University, Silchar are acting as Coordinator and Deputy Coordinator of the Centre. Dr. Pankaj Chetia is working as Research Associate of the Centre. |
| |
 |
Participants during a Hands on Training Session of a Bioinformatics Workshop |
| |
| |
Contacts |
| |
Bioinformatics Centre
1st Floor, Department of Life Science & Bioinformatics
Assam University, Silchar-788011
Assam, India
Phone/Fax: +91-3842-270920
email: aunivsilchar.btisnet@nic.in
bioinfoaus@bioinfoaus.ac.in
Website: www.bioinfoaus.ac.in |
|
|
