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BTISNET - Bioinformatics Infrastructure Facility
    The DBT-BIF centre at university of Kerala work as a part of Centre for Bioinformatics established in 2005 and upgraded as the Dept. of Computational Biology and Bioinformatics in 2011.
Major research activities    

Current research areas are Genomic & Proteomic Digital Signal Processing, Chaos Game Theory in Bioinformatics, Bio-sequence analysis (Protein trafficking, Exon prediction, Hubness and Knotedness prediction of proteins, small gene identification), Computational Synthetic Biology, Molecular Modeling & drug design, Bio-sequence compression, Venom informatics.
The project on Snake Venom detection Biosensor (SVDB) provides a system and method for detecting quantitative extent of envenomation and to monitor the venom clearance from the body using species specific diagnostic biosensor. Using this technology we can determine dose of monovalent Anti-snake Venom (ASV) required to be administered to the victims bitten by poisonous snake. The digital electronic circuitary has been developed and tested at the bio-chemistry-electronics interface is under development.
To complement the insilico biology work going on at the Department, a well equipped microbiology and bioelectronics lab has been set up recently. This provides complete research facility for microbiology, molecular biology, phytochemistry, bioelectronics and clinical studies. Snake venom detection bio-sensor development, miRNA validation, CR-3 receptor agonist’s longevity study and also on bio-active compound isolation are some of the major projects that are on. With the establishment of the wet lab, a long felt balance of bio and informatics has been achieved

Software developed by the centre are now available on-line:

  • CGRex: A Software for generating CGR Signatures of bio-sequences Developed with DIT, Govt of India support.
  • HumLocoProt is on-line software predicting sub-cellular localization of human proteins, available at
  • Cgress (DNA compression algorithm) available at
  • Repam (Calculating scoring matrices, which is a correct version of parm). available at www.
For more information: Click here
Coordinator :

Dr. Achuthsankar S. Nair
Centre for Bioinformatics, University of Kerala,
Kariavattom, Thiruvananthapuram -695581, India
Phone : 471-2378759(O), 471-2542220

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