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SANT GADGE BABA AMRAVATI UNIVERSITY, AMRAVATI, MAHARASHTRA


About the Bioinformatics Centre
 

The Bioinformatics Infrastructure Facility was established in 2006-07 under the scheme for the promotion of Biology Teaching through Bioinformatics as part of the Biotechnology Information System Network (BTISNET) program of Department of Biotechnology, Government of India. This facility was inaugurated on 28th December 2007 by Hon’ble Vice Chancellor Dr.(Ms) Kamal Singh, in the presence of Dr. Gulshan Wadhwa, Principle Scientific Officer and Information Officer, Apex Centre, DBT, New Delhi. Various training programs have been organized and facility is being used regularly by students, researchers and faculty for open access, books, video lectures and journal on various subjects. The BIF is routinely used by M.Sc. student for accessing web base lectures & practical, web browsing & literature search by the researchers and faculty.

Area of Specialization: Bioinformatics and screening of microbial/plant derived molecules for drug discovery.

Objectives
 
  • To develop human resource in Bioinformatics and Biotechnology.
  • To carry out need based Research.
  • Organize webinar, seminar, Workshop and training programs under BTISNet program.
  • Providing training to students through traineeship and studentship.
  • Promoting education and human resource development in Bioinformatics.
 
Achievements at a glance
 
  • Setting up of High performance cluster based on ROCKS Cluster on Cent OS platform.
  • Developed an Intranet portal for the National level Conference (NCCAB-2013).
  • Provided dedicated computer facility to students and researchers with LAN based portal with collection of books in PDF format and other learning resources.
  • BIF has also extended the network facility to classroom, laboratories of faculties and DST FIST computer laboratory.
  • One server is also providing support to UGC scheme for coaching of SC, ST and Minority Community students for NET and SET for lecturership.
  • i-Bioseminar Series: Weekly one hour lecture series has been started for students and research scholars of Biotechnology, Botany, Zoology and Microbiology Departments.
 
Current areas of Research
 
Validation of Complementary and Alternative Medicine using Bioinformatics approach. Database Development.
 
In-silico study of pharmacological potential from Ganoderma spp.
Natural products have been the source of most of the active ingredients of medicines. From the last decade it has been observed that the drugs launched to the market are of natural origin or new chemical entities based on natural product. The development of natural product-derived drugs poses significant challenges in several areas. Despite a period in which pharmaceutical companies cut back on their use of natural products in drug discovery, there are many promising drug candidates in the current development pipeline that are of natural origin. Among the approximately 250 species belonging to the Ganoderma genus, G. lucidum is the most studied one because of its great medicinal interest. Many physiological functions of G. lucidum have been investigated, mainly anticancer and anti – HIV. However, computational approach greatly helps to explore the therapeutic potential in a mechanistic way. The focus is to provide in-silico recognition of good therapeutic from Ganoderma spp.
 
Anti-Cancerous Herbal Compounds Database (ACHCDb)
India is rich in plant diversity as it has got vastly varying geographical areas right from great Himalayan ranges to planes of Ganges and from Deccan plateau to deserts of Rajasthan. The use of such wide resources has been there for centuries not only in local regions but in distant parts as well. We not only use various plant materials but also worship them for the enormous gifts they provide us. Being an Agriculture based country use of plant materials is profuse here. The Science of using plant products is also started centuries before in India, well known as Ayurveda. Ayurveda has described various plants with their utility as Medicine. In spite having huge heritage the science of Ayurveda is not well supported.  The present database includes over 400 plants described in Ayurveda with their important constituent anti-cancerous compounds and their respective targets. The same is built to study the anti-cancerous activity of Herbal compounds.
 
 
 
Contacts:
 

Dr. Prasad A. Wadegaonkar
Coordinator and Professor  & Head
BTISNET-Bioinformatics Infrastructure Facility, Department of  Biotechnology,
Sant Gadge Baba Amravati University,
Amravati 444 602, Maharashtra
E-Mail: sgbauniv.btisnet@nic.in
prasadwadegaonkar@sgbau.ac.in
Phone Number: 0721-2662207 ext 267
Mobile: 09422157263

   

Mr. Sudarshan D. Kove
Co-coordinator and Assistant Professor

BTISNET-Bioinformatics Infrastructure Facility, Department of Biotechnology,
Sant Gadge Baba Amravati University,
Amravati 444 602, Maharashtra
E-mail: sudarshankove@sgbau.ac.in
Mobile: 09890386031/09421844413

 
 


About the Institution
 

Established on 1st May, 1983, the auspicious Maharashtra Day & Worker’s Day. This University geographically covers the western Vidarbha belt (i.e., five districts – Amravati, Akola, Yavatmal, Buldhana and Washim) of Maharashtra State. The Motto of this University is – “Education for Salvation of Soul’’. The University is recognised under Section 12(B) of UGC Act. The University is also an associate member of Association of Commonwealth Universities, London (U.K.). The University has 10 faculties which include Arts, Commerce, Sciences, Medicine, Ayurved, Education, Social Science, Law, Home Science, Engineering & Technology.
The University has facilities to offer post-graduate & advanced education in Computer, Biotechnology, Business Management, Law & degree courses in Chemical-Technology. University values research as evidence that teaching programmes are underpinned by a solid base of latest knowledge and advanced techniques.

 

“The mission of Sant Gadge Baba Amravati University is to contribute to the society through the pursuite of education, learning and research at the highest level of excellence.”
 

BIF is housed in Department of Biotechnology. Department of Biotechnology was established in 1994 with financial support of State Government and is also recognized certified agency for starting Biotech Industries. Research in Biotechnology is being funded by UGC, DST, DOE, State Govt. etc. Department is also supported by DST-FIST program.
The mission of the Biotechnology Department is to provide its students with an education that establishes a strong foundation and appreciation for understanding the development in the rapidly advancing field of Biotechnology, to develop technical and critical thinking skills necessary for success in the field, to foster ethical behavior, and to promote outreach.

 
Database/applications developed

E-portal (Open access lectures) has been developed which provides links to more than 300 hours video based lectures on Bioinformatics, Biochemistry, Molecular Biology Immunology etc.
E-portal for Teaching elective paper on Drug Discovery http://wprasad.webs.com/drugdiscoveryelective.htm
E-portal for resources generated during last workshop http://wprasad.webs.com/

 
Inter Institutional collaboration
The BIF is routinely used by M.Sc. student for accessing web base lectures & practical, web browsing & literature search by the researchers and faculty of other Life-science Department.
 
Infrastructural Facilities

Servers – 02, Desktops – 22, Network Printer – 01, DeskJet- 01, HP Laser Printer – 01,Scanner – 01, Photocopier -01, Router – 01, 24 port switch-01
Internet through NME-ICT project – 1.0 Gbps,
Software – Geneious, Discovery studio, FlexX, Sigma ScanPro, Prism GraphPad, Visual Studio,
Academic Licences for -ACD/Chemsketch, Chemaxon, Marvin Sketch, VMD, Ligplot
Open source softwares: BIOLINUX-7, AutoDock, Arguslab, Rockscluster, Openbabel, Gromacs, Puppy Linux.

 
Recent publications
 

Wadegaonkar VP, Wadegaonkar PA (2013) Withanone as an inhibitor of survivin: A potential drug candidate for cancer therapy. Journal of Biotechnology Volume 168, Issue 2, 229–233.

 
Yogini A. Ranade, Smita M. Dharmadhikari and Prasad A. Wadegaonkar(2013).Screening, production, purification and characterization of beta-lactamase from uropathogenic E.coli. European Journal of Experimental Biology, 3(1):434-442.
 

Wadegaonkar V.P. and Wadegaonkar P.A. (2012). Withaferin A targets apoptosis inhibitor cIAP1:  A potential anticancer candidate. Journal of Applied Pharmaceutical Science 2(3), 154-157. DOI 10.7324/JAPS.2012.2527

 

Jaiswal J.V. & Wadegaonkar P.A. & Hajare S.W. (2012). The Bioflavonoid Galangin suppresses the Growth of Ehrlich Ascites Carcinoma in Swiss Albino Mice: A Molecular Insight. Appl Biochem Biotechnol. DOI 10.1007/s12010-012-9646-3

 

Hade S.N. (2012). Exploration of new therapeutic potentials of phytoconstituents in anti-inflammatory plants by PASS. Journal of Chemical and Pharmaceutical Research 4 (4), 1925-1937.

 

Wadegaonkar P.A. and Wadegaonkar V.P. (2012).  Withanone as an inhibitor of survivin: A potential drug candidate for cancer therapy. Journal of biotechnology (Impact Factor: 2.88). 08/2013; DOI:10.1016/j.jbiotec.2013.08.028 Source: PubMed

 

Pilley H.H. (2011). In-silico prediction of structural and functional aspects of a hypothetical protein of Capnocytophaga canimorsus CC5. Journal of Advanced Bioinformatics Applications and Research. 2(3), 206-

 

S.R. Deshmukh, S. Habtemariam and P.A. Wadegaonkar (2010). Antioxidant and antiproliferative activity of root suspension culture of Morinda citrifolia L. Res. J. Pharm and Tech, 3(4), 470-473

 

J.V. Jaiswal and P.A. Wadegaonkar (2009) Bioinformatics: A tool for identification of phytochemicals in cancer therapy. Proceedings of 12th Workshop on Biomedical Informatics and Communications. Bioinformatics Centre, MGIMS, Sevagaram. P. 17-20.

Faculty Members
 

Name

Designation

Status

Dr. Prasad A.
Wadegaonkar

Coordinator

Professor-
Biotechnology Department

Mr. Sudarshan D. Kove

Co-coordinator

Asst. Professor-
Biotechnology Department

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